The post examines historical perspectives on decomposition through the writings of a Babylonian scribe, linking them to broader themes of death and the emergence of life.
About:
Abhishaike Mahajan is the author of Owl Posting, a Substack publication featuring essays about biology and machine learning, written for and by owls. The publication has thousands of subscribers.
Website:
Specializations:
Incoming Links:
Subscribe to RSS:
The post questions the reality of the J.P. Morgan Healthcare Conference, suggesting it functions as a social contract within the biopharmaceutical industry, akin to a religious pilgrimage.
The essay discusses the challenges of RNA structure prediction, emphasizing that despite advancements like AlphaFold3, the problem remains unsolved due to the limited number of experimentally determined RNA structures and the inhe...
Yunha Hwang explores the potential of genomic language models to improve the annotation of microbial genomes, addressing the vast unknowns in gene functions.
In this podcast episode, Dr. Ellen Zhong, a computer science professor at Princeton University, discusses her pioneering work in applying machine learning (ML) to cryogenic electron microscopy (cryo-EM) for protein structure deter...
6.6Joining Noetik
2025-06-29 • immunology bio ml cancer research noetik dyno therapeutics
Abhishaike Mahajan shares his transition from Dyno Therapeutics to Noetik, a startup focused on machine learning in biology, particularly in cancer therapeutics. He reflects on his beliefs about the ML-bio field, critiques the cur...
Biosecurity faces significant challenges from bioweapons and agroterrorism, necessitating improved regulations and innovative technologies to enhance detection and prevention efforts.
Co-founders Ben Woodington and Elise Jenkins unveil SOMA, a brain implant that uses electrical stimulation to treat cancer, particularly glioblastoma, by interfacing with the nervous system.
Lab robotics is evolving towards improved automation and integration, with a focus on enhancing experimental quality rather than just increasing throughput.
Neurotechnology requires a deep understanding of multiple fields and presents complex challenges in evaluating its clinical relevance and effectiveness for various patient populations.
Leash Bio is pioneering ethical machine-learning practices in drug discovery, focusing on rigorous data integrity to avoid biases and improve model generalization.
Polyphron aims to revolutionize organ repair by growing human tissue ex-vivo through a process that mimics embryogenesis, leveraging machine learning and chemical perturbations.
The essay discusses the intricate details of cancer, emphasizing that it is a highly complex disease with significant variability in its presentation and treatment. It traces the evolution of cancer understanding from visual patho...
The blog post discusses the application of 'virtual cells' in cancer drug development, particularly focusing on their role in identifying anti-PD-1 responders and refining clinical trial eligibility. It highlights the challenges o...
This essay discusses the importance of understanding off-target effects in drug discovery, highlighting a dataset produced by EvE Bio that maps interactions between FDA-approved drugs and human cellular receptors. The author argue...
The blog post explores the implications of AI on creativity and art, using the Flash game Bubble Tanks as a metaphor for human devotion to creative pursuits. It discusses the overwhelming volume of creative content produced today ...
This blog post features an interview with Hunter Davis, the Chief Scientific Officer and co-founder of Until Labs, a biotech startup focused on organ-scale cryopreservation. The discussion covers the challenges and advancements in...
In this podcast episode, Alan Tomusiak, founder and CEO of Permanence Bio, discusses the importance of DNA protection in the context of aging and cancer prevention. He contrasts his approach of stabilizing the genome to prevent mu...
The post critiques the common narrative that biology is an irresistibly fascinating field, arguing instead that the economic realities and harsh truths of modern medicine often overshadow its allure. It highlights the discomfort a...
The author explores the contrasting attitudes towards life and ambition in New York City and San Francisco, particularly within the biotech community. They reflect on how personal experiences with suffering shape perspectives on l...
The blog post discusses the recent surge in funding for protein foundation model startups, questioning whether these investments were justified. It critiques the common perception that these investments were irrational and explore...
The author reflects on personal experiences and encounters, compiling a series of short stories that range from humorous to surreal. These anecdotes include interactions with strangers at social events, insights into the biotech i...
The blog revisits past predictions in bio-machine learning, evaluating their accuracy and the evolution of the field over the past year, particularly in molecular synthesis.
The text discusses various perspectives and corrections on endometriosis, including improved diagnostic imaging, surgical approaches, pregnancy's effect on the disease, heritability, and prevalence. It also mentions non-hormonal t...